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Webinar #1: Personalized Botox injection guided by HDEMG in treating muscle spasticity, by Yingchun Zhang, Ph.D

Webinar #1 | MAY 20, 2020 16.00 CEST |
by Yingchun Zhang, Ph.D

We are proud to announce our first webinar topic in the TMSi Expert Talks webinar series. Yingchun Zhang, Ph.D will talk about his research with the TMSi Refa in combination with High Density EMG for personalized treatment of muscle spasticity.

About the talk

Intramuscular botulinum toxin (Botox) injection has been used as first-line treatment in focal spasticity management. Current injection guidance is based on anatomical landmarks established in healthy muscles or cadavers, despite studies showing that the innervation zones (IZ) location is altered dramatically by the development of muscle spasticity, which may explain the larger variability in treatment effectiveness of Botox injection. Intramuscular Botox injection is proven to be a relatively safe procedure, yet dose-dependent adverse effects may occur during treatment, such as excessive muscle weakness, atrophy, pain at injection site and spread blockage of off-target muscles and autonomic nerves.

A novel 3-dimensional innervation zone imaging (3DIZI) technique has been successfully developed by Dr. Zhang’s groupto precisely image IZ or NMJ distributions in the 3D muscle space from high-density surface EMG (HD-sEMG) recordings. Our imaging accuracy evaluation studies in both healthy and spastic muscles, and clinical outcome evaluation studies have consistently demonstrated the superior IZ imaging accuracy and robustness of the 3DIZI, showing its feasible use in optimizing the therapeutic outcome of clinical Botox injection. In this presentation, the development of the novel 3DIZI technique will be presented and its clinical applications will be discussed.

About the speaker

Yingchun Zhang, Ph.D is currently an Associate Professor in the Department of Biomedical Engineering at the University of Houston. He received his PhD in Electrical Engineering at Zhejiang University, China, in collaboration with the Department of Biomedical Engineering at the University of Minnesota for biomedical signal processing, mathematical modeling and bioelectrical activity imaging methodologies. He completed his postdoctoral training in biomedical engineering, became a faculty member at the University of Minnesota Medical School. He then took the position as an Assistant Professor in the Department of Biomedical Engineering at the University of Houston in 2012, and was promoted to Associate Professor with tenure in 2018.

About the TMSi Webinar series Expert Talks

TMSi organizes several webinars in the coming period on various applications. The webinars are free of charge and cover a variety of applications you can research using TMSi systems. You may expect talks on a variety of topics, such as clinical applications for high density EMG and EEG. We will announce the talks via our LinkedIn page and website. Registration is free and each session will consist ofapproximately 30 minutes presentation and 15 minutes discussion, for a total of 45 minutes.

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